Table 7

Risk categorization results for six laboratory-based risk scores, each compared to non-laboratory-based risk score, womena
Dataset Number Fr_CVD_08 Fr_CVD_91 Fr_CHD_91 SCORE_h SCORE_l CUORE
Aggregate 9,021 93.9% 94.0% 91.7% 95.8% 95.9% 96.2%
BRISK 357 97.2% 97.8% 97.8% 97.8% 97.8% 97.8%
CRIBSA 646 95.7% 95.4% 94.4% 96.6% 96.9% 97.8%
Mangaung 442 92.7% 92.3% 89.1% 95.9% 95.9% 94.5%
QwaQwa 535 92.1% 91.0% 87.7% 95.5% 95.5% 95.1%
AHA-FS Urban 295 97.3% 97.3% 96.6% 96.6% 96.6% 97.3%
AHA-FS Rural 361 92.8% 92.0% 89.7% 92.6% 92.6% 93.7%
PURE, Urban 539 92.8% 93.2% 89.0% 96.6% 97.0% 95.8%
PURE, Rural 607 94.4% 94.1% 92.1% 97.7% 98.0% 96.4%
KwaZulu-Natal 612 96.7% 97.7% 96.4% 98.2% 98.2% 99.0%
CRISIC 393 94.7% 94.9% 93.7% 97.7% 98.0% 96.5%
Mamre 399 94.0% 93.5% 91.0% 95.5% 96.0% 95.5%
KORIS 3,037 92.8% 92.8% 89.7% 95.1% 95.3% 95.0%
PHOENIX 798 91.2% 90.9% 89.2% 91.9% 92.2% 94.2%
Aggregateb 9,021 97.1% 97.2% 96.3% 98.1% 98.3% 97.9%

a‘Agreement’ based on dichotomous risk categorization corresponding to 10-year Framingham (2008) CVD risk >20%, unless otherwise noted; bthreshold of 10-year Framingham CHD risk >20%. CHD coronary heart disease, CVD cardiovascular disease, Fr Framingham.

Gaziano et al.

Gaziano et al. BMC Medicine 2013 11:170   doi:10.1186/1741-7015-11-170

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