Overlap of VDR ChIP-seq peaks with autoimmune disease-associated regions. Autoimmune disease associated regions are those within 100 kb of SNPs implicated in genome-wide association studies (GWAS) at P<10-7. 25(OH)D ≥75,samples with 25-hydroxyvitamin D ≥75 nM, 25(OH)D <75, samples with 25-hydroxyvitamin D <75 nM; ChIP, ChIP-seq, chromatin immunoprecipitation and massively parallel sequencing; VDR, vitamin D receptor.
Handel et al. BMC Medicine 2013 11:163 doi:10.1186/1741-7015-11-163