Table 2

Odds ratios for Clostridium difficile infection and previous depression-related conditions in Medicare beneficiaries
Unadjusted Adjusted for age, gender, race Fully adjusteda
Conditions OR 95% CI P value OR 95% CI P value OR 95% CI P value
Depression
 Yes 1.45 1.14 to 1.86 0.003 1.41 1.10 to 1.82 0.008 1.36 1.06 to 1.74 0.016
 No 1.00 (reference) 1.00 (reference) 1.00 (reference)
Depressive disorders
 Yes 1.44 1.13 to 1.85 0.004 1.40 1.08 to 1.80 0.011 1.35 1.05 to 1.73 0.021
 No 1.00 (reference) 1.00 (reference) 1.00 (reference)
Feeling sad
 Yes 1.62 1.27 to 2.06 <0.001 1.48 1.16 to 1.90 0.002 1.41 1.10 to 1.81 0.008
 No 1.00 (reference) 1.00 (reference) 1.00 (reference)
Emotional, nervous or psychiatric problems
 Yes 1.45 1.02 to 2.05 0.038 1.55 1.08 to 2.21 0.017 1.47 1.02 to 2.11 0.041
 No 1.00 (reference) 1.00 (reference) 1.00 (reference)
Psychiatrist visit
 Yes 1.42 1.10 to 1.83 0.008 1.35 1.05 to 1.72 0.020 1.26 0.95 to 1.67 0.104
 No 1.00 (reference) 1.00 (reference) 1.00 (reference)
Marital status
 Widowed 1.84 1.49 to 2.28 <0.001 1.59 1.26 to 2.02 <0.001 1.54 1.21 to 1.95 0.001
 Divorced/separated 1.63 1.02 to 2.58 0.040 1.66 1.02 to 2.70 0.043 1.54 0.96 to 2.45 0.072
 Single 1.29 0.63 to 2.65 0.473 1.27 0.61 to 2.63 0.518 1.28 0.62 to 2.66 0.499
 Married 1.00 (reference) 1.00 (reference) 1.00 (reference)
Multiple people in household
 Yes 0.67 0.55 to 0.81 <0.001 0.71 0.58 to 0.88 0.002 0.75 0.62 to 0.92 0.007
 No 1.00 (reference) 1.00 (reference) 1.00 (reference)

aAdjusted for year of birth (centered), gender, race, ethnicity, BMI, smoking, end-stage renal disease, Crohn’s disease, celiac disease, ulcerative colitis, irritable bowel disease, number of infection-related visits, total number of medical-related visits, and calendar year of first interview.

Rogers et al.

Rogers et al. BMC Medicine 2013 11:121   doi:10.1186/1741-7015-11-121

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