Table 1

Parameters for disease activity in rheumatoid arthritis, inflammatory bowel disease and psoriasis

Measurement

Definition


Rheumatoid arthritis


Swollen joint count (SJC)

Number of swollen joints as determined by the physician out of a standard set of 28 joints


Tender joint count (TJC)

Number of joints tender to palpation (as for SJC)


Patient assessment of pain

Measured by 100 mm visual analog scale (VAS)


Patient assessment of global disease activity

Measured by 100 mm VAS


Physician assessment of global disease activity

Measured on a six-point scale ranging from 'no activity' to 'maximum activity'


Acute phase reactant

ESR (mm/h) and/or CRP (mg/l)


Health Assessment questionnaire (HAQ)

Assessment of functional status (0 to 3 points)


EuroQol five dimensions utility score (EQ-5D)

Assessment of health-related quality of life (HRQOL) (0 to 1)


Disease Activity Score (DAS28)

Assessment of disease activity computed using SJC, TJC, ESR and patient assessment of global disease activity, based on 28 joints. Termed DAS28-CRP when CRP is used instead of ESR


Inflammatory bowel disease


Hemoglobin level

Measure in g/l


Acute phase reactant

ESR (mm/h) and/or CRP (mg/l)


Harvey Bradshaw Index (HBI)

Assessment of disease activity completed by both patient and physician


Short Health Scale (SHS)

Assessment of HRQOL in four domains, measured by 100 mm VAS


Psoriasis


Psoriasis Area and Severity Index (PASI)

Assessment of extent and severity of skin lesions consisting of four components; scaling, redness, extent and elevation (0 to 72 points)


Dermatology Life Quality Index (DLQI)

Assessment of the effect of skin disease on HRQOL (0 to 30 points)


ESR, erythrocyte sedimentation rate; CRP, C-reactive protein

Lesuis et al. BMC Medicine 2012 10:82   doi:10.1186/1741-7015-10-82

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