Additional file 2.
Smn2B/- mice treated with fasudil show improved gait and movement. A movie of aging fasudil- (left mouse) and vehicle-treated (right mouse) Smn2B/- mice (two months of age). The fasudil-treated mouse displays the agility and ability to freely walk and move around the cage while still displaying a minor neurological phenotype. The vehicle-treated Smn2B/- mouse displays a severe neurological phenotype and reduced motor functions.
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Bowerman et al. BMC Medicine 2012 10:24 doi:10.1186/1741-7015-10-24