Table 1

Baseline characteristics of the risk factors used in the Rotterdam Ischemic Heart Disease and Stroke Computer Simulation (RISC) model for the 3,478 Rotterdam study participants and 25,492 European Prospective Investigation of Cancer (EPIC)-Norfolk study participants

Variable

RISC (n = 3,478)

EPIC (n = 25,492)


Age

69.0 (62 to 75)

59.2 (51 to 67)


Male subjects, %

39%

45%


Smoker


Never

34.5%

46.0%


Former

41.9%

42.3%


Current

23.6%

11.7%


BMI

26.3 (23.8 to 28.5)

26.3 (23.7 to 28.4)


WHR

0.91 (0.84 to 0.97)

0.86 (0.78 to 0.93)


Systolic BP

140.0 (124 to 155)

135.5 (122.5 to 146.5)


Diastolic BP

74.1 (66 to 82)

82.5 (74.5 to 89.5)


Hypertension

36.4%

29.9%


Total cholesterol

6.67 (5.8 to 7.4)

6.19 (5.4 to 6.9)


HDL cholesterol

1.34 (1.1 to 1.5)

1.41 (1.1 to 1.6)


Glucoseb

6.93 (5.5 to 7.5)

6.67 (5.5 to 7.3)


Creatinine

82.5 (72 to 91)

86.7 (76 to 97)


Diabetes mellitus

10.7%

12.2%


Angina pectorisb

10.4%

9.2%


Atrial fibrillationb

2.5%

2.9%


Intermittent claudicationb

2.1%

1.5%


TIAb

5.1%

4.8%


CVD

17.8%

4.3%


Family history of MI

16.3%

18.4%


Family history of CVD

23.0%

23.3%


Abbreviations: BMI, body mass index; BP, blood pressure; CVD, cardiovascular disease; MI, myocardial infarction; TIA, transient ischemic attack; WHR, waist-to-hip ratio.

aAverage values and inter-quartile ranges (brackets) are given for continuous variables, while categorical variables are given as percentages.

bIndicates imputed risk factors for the EPIC-Norfolk dataset.

van Kempen et al. BMC Medicine 2012 10:158   doi:10.1186/1741-7015-10-158

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