Table 1

Demographics for affective disorder (AD)-free patients with diabetes (DM) using oral anti-hyperglycemic agents (OAAs) and their matched counterparts without OAA

Study 1

Study 2


Descriptor

DM without OAAs (n = 21,487)

DM with OAAs (n = 39,159)

Met onlyb (n = 1509)

SUs onlyc (n = 2904)

SUs + Metd (n = 5397)


Age, mean ± SD years

For matched pair

56.0 ± 15.2

57.5 ± 12.3

67.7 ± 9.1

67.7 ± 9.1

65.7 ± 8.9

At DM diagnosis,

56.0 ± 15.2

57.5 ± 12.3

67.5 ± 8.7

67.5 ± 8.7

65.3 ± 8.2

Age groups, years

<50

35.8

28.6

50 to 54

11.9

13.8

6.0

6.8

10.3

55 to 59

11.2

13.9

16.7

16.6

20.2

60 to 64

10.1

13.9

19.3

17.7

20.4

65 to 69

10.4

12.9

18.8

19.4

19.0

≥70

20.6

16.3

39.2

39.6

30.1

Female gender

52.3

48.3

54.5

50.8

52.5

Locality

North

46.5

42.2

54.2

41.8

45.9

Central

22.3

22.8

18.2

20.8

21.4

South

28.3

31.4

26.1

36.2

31.6

East

2.35

2.94

1.5

1.1

1.1

Offshore

0.66

0.66

0

0.10

0.11

Level of health service

Primary

26.7

28.3

26.5

32.2

30.5

Secondary

53.0

47.1

50.6

49.5

51.5

Tertiary

20.3

24.6

22.9

18.3

18.0

Insulin user

0.0

12.3

4.57

3.13

5.78

CCI, mean ± SD

1.4 ± 1.8

1.6 ± 2.1

1.6 ± 2.2


aIn total, there were 9,810 patients with DM who were free of affective disorder (AD) and were on oral anti-diabetic agents (OAA), and who could be matched for age, gender, locality, health service, Charlson Comorbidity Index and DM diagnosis date, with those who were free of AD and who were not on OAA. Where necessary, a patient in the comparison group was used more than once. Thus, there were 9,810 matched pairs. All values are percentages unless indicated.

bPatients diagnosed with DM and treated with metformin,(Met) who had never used insulin during the period 1996 to 2007.

cPatients diagnosed with DM and treated with sulfonylureas (SUs) who had never used insulin during the period 1996 to 2007.

dPatients diagnosed with DM and treated with both Met and SUs, who had never used insulin during the period 1996 to 2007.

Wahlqvist et al. BMC Medicine 2012 10:150   doi:10.1186/1741-7015-10-150

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