Table 2

Standardized scores (%) on the Appraisal of Guidelines, Research and Evaluation (AGREE) instrument assigned to the 13 guidelines.

Domain number (name)


1 (Scope and purpose)

2 (Stakeholder involvement)

3 (Rigour of development)

4 (Clarity and presentation)

5 (Applicability)

6 (Editorial independence)


National Cancer Comprehensive Network1 [2]

92.6

63.9

50.8

83.3

7.4

100.0


Ministry of Health, Singapore2 [15]

7.4

47.2

12.7

69.4

25.9

0.0


American College of Obstetricians and Gynecologists1 [16]

100.0

44.4

33.3

77.8

18.5

0.0


Insitute for Clinical Systems Improvement1 [17]

74.1

50.0

52.4

80.6

55.6

55.6


New Zealand Guidelines Group2 [18]

81.5

75.0

81.0

100.0

85.2

100.0


American Cancer Society (MRI)1 [19]

96.3

52.8

65.1

86.1

44.4

0.0


National Society of Genetic Counselors1 [20]

100.0

41.7

69.8

72.2

44.4

50.0


University of Michigan1 [21]

92.6

8.3

39.7

80.6

0.0

88.9


Towards Optimized Practice Alberta2 [22]

74.1

33.3

7.9

69.4

18.5

0.0


National Health System2 [23,24]

88.9

75.0

87.3

88.9

77.8

50.0


U.S. Preventive Services Task Force2 [25]

96.3

72.2

69.8

86.1

3.7

50.0


Scottish Intercollegiate Guidelines Group2 [26]

96.3

50.0

96.8

86.1

88.9

72.2


American Cancer Society1 [27]

92.6

47.2

52.4

55.6

11.1

50.0


1Independent body/no endorsement,.

2National/state endorsement,

Simone et al. BMC Medicine 2012 10:143   doi:10.1186/1741-7015-10-143

Open Data