Table 3

Predictors of case fatality among children with severe pneumonia, Mulago Hospital, Ugandaa

Variable

RR (Unadjusted) 95% CI

RR (adjusted)b 95% CI

RR (adjusted)c 95% CI


Zinc adjunct therapy

0.3 (0.1,0.8)

0.3 (0.1, 0.97)

0.2 (0.0, 1.1)

WHZ

<-2SD

0.29 (0.1, 0.6)

0.3 (0.1, 0.8)

0.3 (0.1, 0.7)

Oxygen saturation

< 92%

2.4 (1.1, 5.1)

1.6 (0.6, 3.9)

1.4 (0.6, 3.3)

HIV status

Positive

2.7 (1.1, 6.6)

2.6 (1.0, 6.7)

4.3 (1.4, 12.7)

Age

6 to 12

1.0 (0.5, 2.0)

13 to 24

0.1 (0.0, 1.1)

Caretaker relationship to child

Other

0.8 (0.2, 3.2)

Blood culture positive

1.8 (0.6, 6.0)

Zinc adjunct therapy* HIV statusd

5.5 (0.5, 58.3)


a CI, confidence interval

b Only variables with a P-value less than 0.25 in the unadjusted analysis were included in this model.

c Model includes variables with a P-value less than 0.25 and the interaction term for HIV status and Zinc

d Cross-product (interaction) term for HIV status and zinc

Srinivasan et al. BMC Medicine 2012 10:14   doi:10.1186/1741-7015-10-14

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