Effect of catalase (CAT) overexpression on LeTx-induced cardiomyocyte mitochondrial damage. A: Representative fluorescent images of JC-1 in control and LeTx exposure conditions. CCCP (10 μM) was used as a positive control; B: Summarized JC-1 ratio representing mitochondrial membrane potential in response to LeTx and CCCP exposure; and C: Cardiomyocyte mitochondrial membrane potential over time. Mean ± SEM, n = 6 isolations per group, *P <0.05 vs. WT group, #P <0.05 vs. WT-LeTx group.
Kandadi et al. BMC Medicine 2012 10:134 doi:10.1186/1741-7015-10-134