Individual differences and evidence-based psychopharmacology
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BMC Medicine 2012, 10:110 doi:10.1186/1741-7015-10-110Published: 27 September 2012
Individual differences in response to pharmacologic treatment limits the usefulness of mean data obtained from randomized controlled trials. These individual differences exist even in genetically uniform inbred mouse strains. While stratification can be of value in large studies, the individual patient history is the most effective currently available guide for personalized medicine in psychopharmacology.