The different conformations of the acetylcholine binding protein from Lymnaea stagnalis. Portions of the protein have been removed to facilitate visualization. (a) The protein in a closed conformation with nicotine bound (PDB ID: 1UW6), shown in blue. (b) The protein in an open conformation (PDB ID: 1YI5) with the same nicotine conformation superimposed on the structure, shown in pink. (c) Ribbon representations of the two conformations.
Durrant and McCammon BMC Biology 2011 9:71 doi:10.1186/1741-7007-9-71