Figure 5.

Model showing the proposed relationship between Myc and the insulin and TOR signaling pathways. AA: amino acids; DILPs: Drosophila insulin-like peptides; IRS: insulin-receptor substrate; PI3K: phosphatidylinositol-3 kinase; Rheb: Ras homolog enriched in brain; S6K: p-70-S6 ribosomal protein kinase; TSC: tuberous sclerosis complex; TOR: target of rapamycin.

Parisi et al. BMC Biology 2011 9:65   doi:10.1186/1741-7007-9-65
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