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Open Access Research article

The conservation and uniqueness of the caspase family in the basal chordate, amphioxus

Liqun Xu, Shaochun Yuan, Jun Li, Jie Ruan, Shengfeng Huang, Manyi Yang, Huiqing Huang, Shangwu Chen, Zhenghua Ren and Anlong Xu*

Author Affiliations

State Key Laboratory of Biocontrol, National Engineering Research Center of South China Sea Marine Biotechnology, Department of Biochemistry, College of Life Sciences, Sun Yat-sen University, 135 West Xingang Road, Guangzhou, 510275, PR China

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BMC Biology 2011, 9:60  doi:10.1186/1741-7007-9-60

Published: 21 September 2011

Additional files

Additional file 1:

Alignment of caspase domain sequences among bbtCaspase3-like, amphiCASP-3/7, human caspase-3 and caspase-7.

Format: DOC Size: 996KB Download file

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Open Data

Additional file 2:

Alignment of DED sequences among bbtCaspases, bbtFADDs and bbtASCs.

Format: DOC Size: 52KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional file 3:

Alignment of caspase domain sequences between bbtCaspase-8 and hsCaspase-8.

Format: DOC Size: 34KB Download file

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Open Data

Additional file 4:

BbtCaspase-1/2 did not co-localize with bbtCRADD in HeLa cells.

Format: DOC Size: 210KB Download file

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Open Data

Additional file 5:

Alignment of DD sequences among bbtCaspase-1/2, bbtFADD1 and bbtFADD2.

Format: DOC Size: 42KB Download file

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Open Data

Additional file 6:

Time-lapse video of overlay fluorescences of a HeLa cell co-transfected with bbtCaspase-1/2-GFP and bbtASC-RFP. The video was filmed using a Zeiss microscope for 2 h, and it started filming at 6 h after transfection.

Format: MPEG Size: 624KB Download file

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Open Data

Additional file 7:

The same video showing only the green channel, bbtCaspase-1/2-GFP.

Format: MPEG Size: 618KB Download file

Playing the movie within this page requires QuickTime 6.4 or later and JavaScript. Read more

Open Data