Email updates

Keep up to date with the latest news and content from BMC Biology and BioMed Central.

Journal App

google play app store
Open Access Open Badges Commentary

Butterfly eyespot serial homology: enter the Hox genes

James Castelli-Gair Hombría

Author Affiliations

CABD, CSIC/Universidad Pablo de Olavide, Carretera de Utrera km 1, Seville, 41013, Spain

BMC Biology 2011, 9:26  doi:10.1186/1741-7007-9-26

Published: 28 April 2011


Hox genes modify serial homology patterns in many organisms, exemplified in vertebrates by modification of the axial skeleton and in arthropods by diversification of the body segments. Butterfly wing eyespots also appear in a serial homologous pattern that, in certain species, is subject to local modification. A paper in EvoDevo reports the Hox gene Antp is the earliest known gene to have eyespot-specific expression; however, not all Lepidoptera express Antp in eyespots, suggesting some developmental flexibility.

See research article: webcite