Genome-wide association studies in Plasmodium species
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BMC Biology 2010, 8:90 doi:10.1186/1741-7007-8-90Published: 13 July 2010
Genome-wide association studies (GWAS) look for correlations between traits of interest and genetic markers spread throughout the genome. A recent study in BMC Genetics has found that populations of the malaria parasite Plasmodium vivax should be amenable to GWAS searching for a genetic basis of parasite pathogenicity. Geographical substructure in populations may, however, prove a problem in interpreting the results.