Sequence logo comparison of classical Gram-positive bacteriocin and nitrile hydratase leader peptides (NHLP)/Nif11-derived peptides (N11Ps). (A) Logo depiction of TIGR01847, which is representative of the sequence found near the peptide cleavage site of Gram-positive bacteriocins. (B) Logo for the NHLP and N11P families taken together. In addition to the classic Gly-Gly cleavage motif (positions 12-13), the two logos show an abundance of acidic residues at positions 1, 4 and 6 and a significant preference for Leu at position 2 and 7, Ser/Thr at position 3, and either Val/Leu at position 10. This figure was generated online using a published algorithm .
Haft et al. BMC Biology 2010 8:70 doi:10.1186/1741-7007-8-70