Figure 4.

Colinearity between evolutionary age of cancer genes and their role in tumour progression. Parallels between the macroevolutionary origin of the global pathways leading to neoplasia and the developmental timing of mutations in these pathways are shown. The upper part of the figure is adapted from reference [11].

Domazet-LoŇ°o and Tautz BMC Biology 2010 8:66   doi:10.1186/1741-7007-8-66
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