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Open Access Commentary

Altered cell cycle regulation helps stem-like carcinoma cells resist apoptosis

James Chappell and Stephen Dalton*

Author Affiliations

Paul D Coverdell Center for Biomedical and Health Science, Department of Biochemistry and Molecular Biology, University of Georgia, 500 DW Brooks Drive, Athens, GA 30602, USA

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BMC Biology 2010, 8:63  doi:10.1186/1741-7007-8-63

Published: 25 May 2010

Abstract

Reemergence of carcinomas following chemotherapy and/or radiotherapy is not well understood, but a recent study in BMC Cancer suggests that resistance to apoptosis resulting from altered cell cycle regulation is crucial.

See research article: http://biomedcentral.com/1471-2407/10/166 webcite