Smart biomaterials - regulating cell behavior through signaling molecules
Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA 02155, USA
BMC Biology 2010, 8:59 doi:10.1186/1741-7007-8-59Published: 19 May 2010
Important advances in the field of tissue engineering are arising from increased interest in novel biomaterial designs with bioactive components that directly influence cell behavior. Following the recent work of Mitchell and co-workers published in BMC Biology, we review how spatial and temporal control of signaling molecules in a matrix material regulates cellular responses for tissue-specific applications.