Table 2

Gene expression distributions characterized via in situ hybridization.

Gene name

Gene symbol

Entrez gene ID

Brain region

MS


Area X

LMAN

HVC

RA

ME/PIT

POA

HP

S

TN

MHYP


Adenylate cyclase activating polypeptide 1 (pituitary)

ADCYAP1

100225028

-

-

-

Neuropeptide VF precursor (gonadotropin-inhibitory hormone)

NPVF

100038821

-

-

-

-

-

-

-

-

-

Proenkephalin

PENK

100190068

-

-

-

-

-

-

Carboxypeptidase N, polypeptide 2

CPN2

100222124

-

-

-

-

-

*

Chromogranin B (secretogranin 1)

CHGB

100230980

-

-

Hypocretin (orexin) neuropeptide precursor

HCRT

100225610

-

-

-

-

-

-

-

*

Mesotocin-neurophysin I

MST

100220528

-

Neuropeptide Y

NPY

100232180

-

-

-

Neurotensin

NTS

100190409

-

-

-

-

-

Proopiomelanocortin

POMC

100219426

-

-

-

-

-

Somatostatin

SST

100219295

-

-

-

Tachykinin, precursor 1

TAC1

100227778

-

-

-

-

-

Vasoactive intestinal peptide

VIP

100217965

-

-

-

Cerebellin 1 precursor

CBLN1

unpredicted

-

-

-

*

Phosphatidylethanolamine binding protein 1

PEBP1

100190590

-

-

-

*


The distributions of 15 genes have been determined via in situ hybridization (ISH), with the distribution of expression being highlighted in four major song nuclei (Area X, LMAN, HVC, RA) and other behaviorally-relevant brain areas. For each specific brain region, a check mark (√) indicates detected by ISH and a dash (-) indicates no expression as characterized by ISH. In the mass spectrometry (MS) column, a check mark (√) indicates confirmation via MS and an asterisk (*) indicates their homologues are identified in other species. Abbreviations used for non-song control brain areas: ME/PIT-median eminence or pituitary; POA-preoptic area; HP-principle cells of the hippocampus; S-septal nuclei; TN-nucleus taeniae; MHYP-ventromedial hypothalamic nucleus or paraventricular nucleus.

Xie et al. BMC Biology 2010 8:28   doi:10.1186/1741-7007-8-28

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