Table 2

Top 20 gene families expanded in the course of 2Ra

TreeFam ID

Number of duplication nodes

Description


TF106341

19

T-box TF

TF105391

13

Integrin, alpha

TF106499

11

Gonadotropin-releasing hormone receptor/arginine vasopressin receptor

TF101109

10

Cell division control protein 42 homolog

TF105310

10

Wingless-type MMTV integration site family

TF105452

10

Annexin

TF106408

10

PDZ and LIM domain protein

TF105128

8

Dual-specificity phosphatase 3/14/18/19/21/26

TF102004

7

Protein kinase A/C

TF102023

7

Caspase family, apoptosis-related cysteine protease

TF105094

7

Cytochrome P450, family 11/24/27

TF105122

7

Dual-specificity phosphatase 1/2/4-7/9/10

TF105049

6

Heat shock 27-kDa protein/crystallin, alpha

TF105100

6

Mitogen-activated protein kinase 8-14

TF105191

6

ATP-binding cassette, subfamily A (ABC1), member 1-4/7/12/13

TF105392

6

Integrin, beta

TF101079

5

Septin 1/2/4/5/7

TF102003

5

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide

TF102031

5

Phosphoinositide 3-kinase, class I/II

TF105272

5

B-cell translocation gene


aFamilies which underwent expansion consist predominantly of genes encoding TFs and signalling proteins. 2R, two rounds; MMTV, mouse mammary tumor virus.

Huminiecki and Heldin BMC Biology 2010 8:146   doi:10.1186/1741-7007-8-146

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