Klf5-specific targets. Comparison of gene expression changes following KD of Klf2, Klf4 or Klf5 in ESCs. Klf2, Klf4, Klf5 or NS siRNA were transfected in ESCs. RNA samples were collected 12 hr after transfection and subjected to qPCR. (a) Klf5-activated genes. (b) Klf5-repressed genes. Arrowheads indicate the expression changes induced by Klf5 only. All data are expressed as fold changes relative to siNS transfected cells. Error bars represent SD of triplicates.
Parisi et al. BMC Biology 2010 8:128 doi:10.1186/1741-7007-8-128