Table 1

Upregulation/downregulation ratios

Biological process

1 day

4 days

7 days


Signaling associated (34)

0.72

1.72

2.75


Ca2+ binding and translocation (17)

0.36

0.63

1.29


Transcription and translation (78)

0.79

1.52

2.04


Transcription (58)

0.66

1.08

1.65


Chromatin associated (14)

1.60

1.60

1.40


Transcription factors (21)

0.9

1.57

2.00


mRNA processing (23)

0.24

0.62

1.50


Translation (20)

1.50

7.00

4.00


Ribosomal proteins (13)

2.33

9.00

3.33


Translation factors (7)

0.67

5.00

6.00


Cytoskeleton (68)

0.42

0.31

0.42


Muscle (23)

0.18

0.00

0.04


Non-muscle proteins (45)

0.58

0.60

0.85


Motility, shape, structural integrity (25)

0.28

1.00

1.44


Intracellular Movement (10)

1.00

0.11

0.33


Adhesion (5)

1.50

1.50

1.50


Other (5)

3.00

0.66

0.66


Extracellular matrix (19)

2.00

1.83

1.29


Metabolism (33)

0.35

0.29

0.45


Oxidative phosphorylation (8)

0.33

0.17

0.14


Glycolysis (8)

0.33

0.14

0.33


Glycogen (2)

0.00

0.00

0.00


Other (15)

0.44

0.75

1.00


Cell protection (35)

0.47

1.00

2.30


Inflammation related (7)

1.00

2.50

2.50


Apoptosis related (13)

0.25

0.71

1.40


Chaperones (15)

0.50

0.88

3.70


Degradation (11)

0.86

1.00

2.00


Cell cycle (14)

1.00

0.86

1.20


Ratio of proteins upregulated and downregulated for biological process categories at 1, 4, and 7 days post amputation (dpa). Numbers in parentheses represent numbers of proteins in each category.

Rao et al. BMC Biology 2009 7:83   doi:10.1186/1741-7007-7-83

Open Data