Open Access Research article

Proteomic analysis of blastema formation in regenerating axolotl limbs

Nandini Rao1, Deepali Jhamb2, Derek J Milner3, Bingbing Li1, Fengyu Song4, Mu Wang5, S Randal Voss6, Mathew Palakal2, Michael W King5, Behnaz Saranjami1, Holly LD Nye3, Jo Ann Cameron3 and David L Stocum1*

Author Affiliations

1 Department of Biology and Center for Regenerative Biology and Medicine, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA

2 School of Informatics and Center for Regenerative Biology and Medicine, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA

3 Department of Cell and Developmental Biology, and Regeneration Biology and Tissue Engineering Theme, Institute for Genomic Biology, University of Illinois-Urbana Champaign, Urbana, IL, USA

4 Department of Oral Biology, School of Dentistry and Center for Regenerative Biology and Medicine, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA

5 Department of Biochemistry, School of Medicine and Center for Regenerative Biology and Medicine, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA

6 Department of Biology and Spinal Cord and Brain Injury Center, University of Kentucky at Lexington, Lexington, KY, USA

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BMC Biology 2009, 7:83  doi:10.1186/1741-7007-7-83

Published: 30 November 2009

Additional files

Additional file 1:

Statistically significant priority 1 and 2 proteins. Each peptide is listed with its priority number, accession number, gene name, protein name, peptide sequence and maximum fold change (MFC). Proteins identified by axolotl ESTdb are in bold.

Format: XLS Size: 97KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 2:

Fold changes of 309 priority 1 and 2 proteins at 1, 4 and 7 days post amputation (dpa) relative to control for all categories of biological process. Minus indicates negative fold change; otherwise the fold change is positive. NC = no change.

Format: XLS Size: 79KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data