Research article
Genetical genomic determinants of alcohol consumption in rats and humans
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* Corresponding author: Boris Tabakoff boris.tabakoff@ucdenver.edu
1 Department of Pharmacology, University of Colorado, Denver, Aurora, CO, USA
2 Department of Pharmacology, University of California San Diego, La Jolla, CA, USA
3 Department of Pediatrics, University of California Irvine, Irvine, CA, USA
4 Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA
5 Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, CA, USA
6 Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA
7 Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN, USA
8 Max Delbrück Center for Molecular Medicine, Berlin, Germany
9 Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic
10 MRC Clinical Sciences Centre, London, UK
11 Department of Psychiatry, McGill University, Montreal, Quebec, Canada
12 Drug Health Services, Royal Prince Alfred Hospital, Sydney Medical School, University of Sydney, New South Wales, Australia
13 Queensland Institute of Medical Research, Queensland, Australia
14 School of Medicine, University of Queensland, Brisbane, Queensland, Australia
15 Division of Epidemiology, National Institute on Alcohol Abuse and Alcoholism, Rockville, MD, USA
16 Department Psychology-Neuroscience, University of Massachusetts Amherst, Amherst, MA, USA
17 Applied Biosystems, Lingley House, 120 Birchwood Blvd., Warrington, Cheshire, WA3 7QH, UK
BMC Biology 2009, 7:70 doi:10.1186/1741-7007-7-70
Published: 27 October 2009Additional files
Additional file 1:
Supplemental Methods and Results. Table S1: Identification of transcription factors in eQTL on chromosome 6. Table S2: Distribution of covariates used for multivariate model with human subjects. Table S3: Demographic characteristics of human subjects. Table S4: Haplotype frequencies and association with alcohol consumption in human subjects. Figure S1: Alcohol consumption levels in human subjects. Figure S2: Haplotype block assessments. Figure S3: Relationship between alcohol consumption and alcohol dependence in human subjects.
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