Subcellular pH and pH-dependent properties. (a) The average over subcellular compartments of predicted folded form pI, plotted against subcellular pH, with R2 = 0.44. (b) The pH of maximal folded state stability, averaged over proteins for each subcellular location, is plotted against subcellular pH, R2 = 0.84. For both panels, the line of property = pH is marked (rather than the best fit line).
Chan and Warwicker BMC Biology 2009 7:69 doi:10.1186/1741-7007-7-69