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Open Access Highly Accessed Research article

Mutations in many genes affect aggressive behavior in Drosophila melanogaster

Alexis C Edwards125, Liesbeth Zwarts4, Akihiko Yamamoto23, Patrick Callaerts4 and Trudy FC Mackay12*

Author Affiliations

1 Department of Genetics, North Carolina State University, Raleigh, NC, USA

2 W. M. Keck Center for Behavioral Biology, North Carolina State University, Raleigh, NC, USA

3 Department of Biology, North Carolina State University, Raleigh, NC, USA

4 Laboratory of Developmental Genetics, VIB-PRJ8 & Katholieke Universiteit Leuven, Center for Human Genetics, Leuven, Belgium

5 Current address: Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Department of Psychiatry, Richmond, VA, USA

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BMC Biology 2009, 7:29  doi:10.1186/1741-7007-7-29

Published: 11 June 2009

Additional files

Additional file 1:

Mean aggression scores (MAS) of 170 P{GT1} insert lines. This file shows the results of the screen of 170 P-element insert lines for alterations in aggressive behavior, the genes tagged by the P-elements, the mean aggression scores and effects, and gene ontology information.

Format: XLS Size: 57KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 2:

Human diseases associated with P{GT1} insertions in Drosophila genes with aberrant aggressive behavior. This file shows the P-element insert lines with altered aggressive behavior, their mean aggression scores, and diseases in which the human orthologues of the tagged genes have been implicated.

Format: XLS Size: 34KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data