Table 1

Phenotypes of Pygo2 wild-type, heterozyogous, and null E18.5 embryos on a Pygo1 null background.

Pygo2+/+

Pygo2+/-

Pygo2-/-


Sample size

6

14

10

Observed phenotypes

Average weight (g)

1.36

1.33

0.97 *

Cleft palate

0

0

6

Exencephaly

0

0

2

Lens defect

0

0

10

Reabsorption/in utero death

0

0

2


* Denotes a significant change (p < 0.01) of the average weight of the Pygo2 null group compared with both the Pygo wild-type and heterozygous groups.

Schwab et al. BMC Biology 2007 5:15   doi:10.1186/1741-7007-5-15

Open Data