Table 2

TCRα and β chain repertoires of a Th2 polarized T cell line
CDR3 region CDR3 length %
TCR alpha SDSAKYFC ALEGIASSSFSKLV FGQG 14 24
GDSAAYFC AVRGTNAYKVI FGKG 11 16
SDSALYYC ALSDANNYAQGLT FGLG 13 14
GDSAAYFC AAGDTNTGKLT FGDG 11 10
EDSAIYFC AASRGNMGYKLT FGTG 12 8
GDSAAYFC AALNTNTGELT FGDG 11 6
SDSAVYYC ALVRDTGYQNFY FGKG 12 4
SDSAVYYC ALGEDTNAYKVI FGKG 12 4
SDSAVYYC ALGFQGGRALI FGTG 11 4
GDSAMYFC AAPPMNYNQGKLI FGOG 13 4
TDSGTYFC AMERODNYAOGLT FGLG 13 2
EDSGTYFC AADNRIF FGDG 31 2
SDSAVYYC ALGDREGGRALI FGTG 15 2
TCR beta QDSAVYLC ASSFQTGGAETLY FGSG 13 6
NEMAVFLC ASSSPTGGWNAEQF FGPG 14 6
EDSAVYLC ASSNYAEQF FGPG 9 6
DDSATYFC ASSLGTGDAEQF FGPG 12 6
DDSATYFC ASSLRDNGDTQY FGPG 12 6
DDSATYFC ASSOEAGGVDTQY FGKG 13 4
NEMAVFLC ASSPRTTSGNTLY FGEG 13 4
NEMAVFLC ASSPPTGSPNERLF FGHG 14 4
EDRGLYLC GARDLWGGKNTLY FGAG 13 4
DDSATYFC ASSQEGLDSYEQY FGPG 13 4
NEMAVFLC ASSIEDSGTEVF FGKG 12 4
QDSAVYLC ASSLRGHTEVF FGKG 11 2
ODSAVYLC ASSVRDWGDTQY FGPG 12 2
QDSAVYLC ASSLRNTEVF FGKG 10 2
DDSATYFC ASSQEGWGPYEQY FGPG 13 2
DDSATYFC ASSQGLGNYAEQF FGPG 13 2
DDSATYFC ASSQEGTGGYAEQF FGPG 14 2
DDSATYFC ASSQDGTGGYAEQF FGPG 14 2
DDSATYFC ASSQGIYEQY FGPG 10 2
DDSATYFC ASSPANSDYT FGSG 10 2
DDSATYFC ASSQDGTIODTQY FGPG 13 2
DDSATYFC ASSPDWDTTGQLY FGEG 13 2
DDSATYFC ASSQDRSSSAETLY FGSG 14 2
DDSATYFC ASSQEGTGGKEQY FGPG 13 2
NEMAVFLC ASSSPTGGWNAWQF FGPG 14 2
EDSAVYLC ASSPRGLYAEQF FGPG 12 2
EDSAVYLC ASSRDWGSEQY FGPG 11 2
EDSAVYLC ASSPDWGDEQY FGPG 11 2
SQTAVYFC ASSGRTTANTEVF FGKG 13 2
SQGRTLYC TCSADGSYEQY FGPG 11 2
EYSAMYLC ASSSGGFAETLY FGSG 12 2
EYSAMYLC ASRDWGETLY FGSG 10 2
SHSGFYLC AWSLWSGVANERLF FGHG 14 2
SQTSLYFC ASSDFSTEVF FGKG 10 2

The most dominant TCR alpha sequence is shown in bold.

Mean CDR3α length 12.24 ± 0.20 (SE) (n = 49).

Mean CDR3β length 12.25 ± 0.20 (SE) (n = 51).

Reynolds et al.

Reynolds et al. BMC Biology 2014 12:32   doi:10.1186/1741-7007-12-32

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