Early postnatal pruning of retinal inputs to the thalamus. During the first postnatal week (left), RGC axons find their appropriate target in the lateral geniculate nucleus following gradients of molecular guidance cues. Axons from both eyes are sparsely branched and cover large areas of the lateral geniculate nucleus where they overlap extensively. By the end of the third postnatal week (right), RGC axon terminals refine to increase the precision of the visual map, produce denser projections and segregate into eye-specific domains.
Benjumeda et al. BMC Biology 2014 12:3 doi:10.1186/1741-7007-12-3