Phases of viral decay under treatment. When treatment is initiated, plasma viral load undergoes a multiphasic decay, with slower rates of viral loss as treatment progresses. One possible explanation is that there are various classes of infected cells (Figure 1) with different turnover rates. This phenomenon makes it very difficult to predict whether viral eradication is possible and how long it would take.
Perelson and Ribeiro BMC Biology 2013 11:96 doi:10.1186/1741-7007-11-96