Comparison of the effects of Spalax, Acomys, Heterocephalus and rat skin fibroblasts on growth of Hep3B cells. Hep3B tumor cells were cultured either alone or in presence of Spalax, Acomys, Heterocephalus or rat fibroblasts in the ratio of 1:10 (5 × 104 fibroblasts and 5 × 103 cancer cells in six-well plates) in RPMI/DMEM-F12 media (1:1) containing 10% FBS. After seven days incubation cells were photographed. Representative images for each sample are shown (×200). White arrows point to the foci of damaged cancer cells. TC, tumor cells.
Manov et al. BMC Biology 2013 11:91 doi:10.1186/1741-7007-11-91