Distribution of differences in the NS5B region. Sequences were compared with a 229-nucleotide (nt) fragment of the NS5B gene derived from the presumed source (PS). The graph shows the distribution of nucleotide differences (Hamming’s distance) for sequences derived from patients included in the outbreak (red bars), from patients excluded (dark purple) from the outbreak, and from local controls (grey). The inset shows the same distribution for putative outbreak samples (dark blue) and local controls (gray) before the former were divided into included and excluded from the outbreak.
González-Candelas et al. BMC Biology 2013 11:76 doi:10.1186/1741-7007-11-76