Expression pattern of Shh pathway-related genes in Gas1-/-mutants. At E10.5, the expression patterns of Shh, Bmp4, Bmp2, Fgf8 and Fgf10 are similar in wild-type and Gas1-/- mutant mice. The expression territory of Ptch1 and Gli1 are nevertheless reduced posteriorly and apically within Rathke’s pouch. H&E, hematoxylin and eosin.
Khonsari et al. BMC Biology 2013 11:27 doi:10.1186/1741-7007-11-27