Table 7

One-way ANOVA results comparing muscle and liver mRNA levels between cold-acclimated normal thyroid, hypothyroid, and T2-supplemented or T3-supplemented fisha
Muscle Liver
Gene F d.f. P F d.f. P
PGC1α 10.233 3, 25 <0.001** 1.791 3, 39 0.165
PGC1β 2.202 3, 34 0.106
PPARδ 1.202 3, 38 0.322
NRF1 0.731 3, 29 0.542
NRF2a 1.272 3, 21 0.310
NRF2b 0.714 3, 23 0.554
COX Vb2 6.858 3, 28 0.001** 2.440 3, 21 0.093
ATPase A 2.422 3, 30 0.085
ATPase B 3.380 3, 29 0.032*
COX II 3.705 3, 23 0.026*
ATP 8/6 5.530 3, 29 0.004**

Abbreviations: ATPase A, F0F1-ATPase subunit A; ATPase B, F0F1-ATPase subunit B; ATPase 8/6, F0F1-ATPase subunits 8 and 6; COX II, Cytochrome c oxidase subunit 2; COX Vb2, Cytochrome c oxidase subunit 5b2; d.f. degrees of freedom; NRF1, Nuclear respiratory factor 1; NRF2a, Nuclear respiratory factor 2a; NRF2b, Nuclear respiratory factor 2b; PGC1α, Peroxisome proliferator-activated receptor γ coactivator 1-α; PGC1β, Peroxisome proliferator-activated receptor γ coactivator 1-β; PPARδ, Peroxisome proliferator-activated receptor δa and δb.

aMissing values represent genes that were not sensitive to TH in the cold-acclimated and warm-acclimated normal thyroid and hypothyroid fish, and therefore were not analyzed in cold-acclimated normal thyroid, hypothyroid, and T2-supplemented or T3-supplemented fish.

*P<0.05.

**P<0.01.

Little et al.

Little et al. BMC Biology 2013 11:26   doi:10.1186/1741-7007-11-26

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