Table 5

Two-way permutational multivariate analysis of variance (PERMANOVA) results comparing liver mRNA levels between cold-acclimated and warm-acclimated normal thyroid and hypothyroid fish
Acclimation temperature Thyroid status Acclimation temperature × thyroid status
Gene F d.f. P F d.f. P F d.f. P
PGC1α 13.672 1, 32 0.001** 2.597 1, 32 0.095 1.521 1, 32 0.238
PGC1β 26.692 1, 29 0.001** 1.191 1, 29 0.274 6.374 1, 29 0.011*
PPARδ 25.657 1, 31 0.001** 1.128 1, 31 0.324 6.139 1, 31 0.010*
NRF1 32.817 1, 26 0.001** 0.784 1, 26 0.400 3.464 1, 26 0.050*
NRF2a 7.869 1, 22 0.004** 1.163 1, 22 0.290 5.015 1, 22 0.020*
NRF2b 15.085 1, 24 0.001** 0.578 1, 24 0.497 6.708 1, 24 0.017*
COX Vb2 9.789 1, 20 0.005** 3.490 1, 20 0.049* 0.336 1, 20 0.672
ATPase A 23.119 1, 32 0.001** 0.292 1, 32 0.713 1.109 1, 32 0.308
ATPase B 6.456 1, 33 0.007** 0.097 1, 33 0.942 1.604 1, 33 0.189
COX II 6.458 1, 22 0.007** 1.240 1, 22 0.295 6.377 1, 22 0.013*
ATP 8/6 4.056 1, 21 0.06 0.422 1, 21 0.571 3.904 1, 21 0.044*

Abbreviations: ATPase A, F0F1-ATPase subunit A; ATPase B, F0F1-ATPase subunit B; ATPase 8/6, F0F1-ATPase subunits 8 and 6; COX II, Cytochrome c oxidase subunit 2; COX Vb2, Cytochrome c oxidase subunit 5b2; d.f. degrees of freedom; NRF1, Nuclear respiratory factor 1; NRF2a, Nuclear respiratory factor 2a; NRF2b, Nuclear respiratory factor 2b; PGC1α, Peroxisome proliferator-activated receptor γ coactivator 1-α; PGC1β, Peroxisome proliferator-activated receptor γ coactivator 1-β; PPARδ, Peroxisome proliferator-activated receptor δa and δb.

*P<0.05.

**P<0.01.

Little et al.

Little et al. BMC Biology 2013 11:26   doi:10.1186/1741-7007-11-26

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