MST1 is expressed in striated muscles and enriched at early stage of postnatal muscle development. A. Expressions of MST1/2 and FOXO3a in striated muscles from three-month-old adult wild type mice were identified by Western blotting. B-D. Densitometry analysis showed the expressions of MST1/2 kinases were enriched in cardiac muscle, diaphragm as well as soleus muscles, which contain significant amount of type I fibers. E. Representative blotting shows protein level of MST1 was decreased during postnatal development in diaphragm, cardiac, TA and soleus muscles. F. Quantification of muscular MST1 expression during postnatal development.
Wei et al. BMC Biology 2013 11:12 doi:10.1186/1741-7007-11-12