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Open Access Research article

Wnt6 is required for maxillary palp formation in Drosophila

Nikolaos Doumpas1, Gáspár Jékely2 and Aurelio A Teleman1*

Author Affiliations

1 German Cancer Research Center (DKFZ), Heidelberg, Germany

2 Max Planck Institute for Developmental Biology, Spemannstrasse 35, 72076 Tuebingen, Germany

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BMC Biology 2013, 11:104  doi:10.1186/1741-7007-11-104

Published: 3 October 2013

Additional files

Additional file 1: Figure S1:

Wnt6KO flies have no detectable Wnt6 mRNA. (A) Quantitative PCR on genomic DNA from control and Wnt6KO flies confirming absence of the Wnt6 knockout region, but not absence of two other unrelated genomic regions (mir-278 and sty), in the knockout flies. (B) Quantitative RT-PCR to detect Wnt6 mRNA levels in control and Wnt6 knockout flies reveals no Wnt6 transcript left in the knockouts. (C-D’) In situ hybridization to detect Wnt6 mRNA in wing discs (C-C’) and eye-antenna discs (D-D’) of control and Wnt6 knockout animals.

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Additional file 2: Figure S2:

Wnt6KO flies lack maxillary palps. (A-C) Scanning electron micrographs showing that Wnt6KO flies (B), unlike control flies (A), lack maxillary palps (positions indicated with arrows).

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Additional file 3:

Oligo sequences.

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Open Data