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Resolution: standard / high Figure 2..
The distribution of fitness effects of new mutations is bimodal (top). While in a partially cryptic state, selection is strong enough to purge the left
mode, while having little effect on the right mode, generating a set of cryptic variants
of greatly enriched quality (bottom).
Masel BMC Biology 2013 11:103 doi:10.1186/1741-7007-11-103 |