Table 4

Cluster analysis summary of transcripts expressed in a region-specific manner along the porcine GI tract.

GI clusters r = 0.9, MCL1.7

Probes

Unique gene IDs

Cluster Expression Profile Description

GI-cluster: Class

GI-cluster: Sub-Class


Cluster003

460

372

Tongue/lower_esophagus

Stratified squamous epithelium

Epithelium

Cluster008

132

114

Tongue>>lower_esophagus

Stratified squamous epithelium

Epithelium

Cluster016

66

52

Stomach/intestine

Columnar epithelial

Epithelium

Cluster005

328

251

Small intestine

Digestion/absorption

Epithelium

Cluster028

21

17

General-higher in fundus/intestine

Epithelial

Epithelium

Cluster021

35

29

Intestine

Intestinal epithelium

Epithelium

Cluster013

93

76

Salivary gland

Stratified columnar epithelium

Epithelium

Cluster025

23

19

Colon specific

Colon epithelial specific function

Epithelium

Cluster029

21

18

Colon>>fundus

Colon epithelial specific function

Epithelium

Cluster040

16

8

Colon>>fundus/small intestine

Colon epithelial specific function

Epithelium

Cluster015

76

65

Salivary gland

Mucous acini

Glandular epithelium

Cluster006

167

135

Salivary gland

Serous acini

Glandular epithelium

Cluster023

26

19

Fundus

Fundic glands

Glandular epithelium

Cluster012

106

89

Fundus>antrum

Mucous neck/gastric glands

Glandular epithelium

Cluster018

61

51

Antrum

Pyloric glands

Glandular epithelium

Cluster031

20

17

Duodenum>fundus>intestine

Complement (crypts/goblet cells)

Glandular epithelium

Cluster014

79

60

Duodenum

Glandular/epithelial

Glandular epithelium

Cluster001

801

653

Ileum>jejunum

B cell/cell cycle

Immune

Cluster039

17

12

Intestine/stomach/salivary

Plasma B cell

Immune

Cluster020

37

30

High in intestine (small>large)/fundus

T cell

Immune

Cluster055

11

6

High in intestine (small>large)/fundus

T cell

Immune

Cluster027

22

16

Stomach/intestine-variable between animals

IFN response

Immune

Cluster033

18

15

Stomach/intestine-variable between animals

Immune response

Immune

Cluster037

17

15

General-higher in stomach/intestine

Immune-related

Immune

Cluster011

122

91

General-higher in stomach/intestine

MHC class 1 antigen presentation

Immune

Cluster022

32

30

General-higher in intestine/stomach

MHC class 2 antigen presentation (immune)

Immune

Cluster026

23

21

Pylorus

Neuronal

Neuronal

Cluster010

124

95

General-higher in pylorus>antrum

Neuronal

Neuronal

Cluster004

456

336

Tongue/upper oesophagus

Skeletal muscle

Muscle

Cluster002

532

382

Pylorus/antrum/oesophagus>>general

Smooth muscle/ECM (Fibroblast)

Muscle

Cluster052

12

9

Esophagus

Cartilage

Muscle

Cluster030

20

17

Tongue/esophagus>pylorus

Muscle-related

Muscle

Cluster009

130

93

General-higher in tongue/u-esophagus/antrum/pylorus

Muscle-smooth/skeletal

Muscle

Cluster007

149

142

General-higher in ileum, rectum

Cell cycle-related

Pathway

Cluster019

58

54

General-higher in small intestine

Histones

Pathway

Cluster017

63

53

General-higher in muscle

Oxidative phosphorylation

Pathway


GI, gastrointestinal.

Freeman et al. BMC Biology 2012 10:90   doi:10.1186/1741-7007-10-90

Open Data