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Open Access Research article

Multiparameter behavioral profiling reveals distinct thermal response regimes in Caenorhabditis elegans

Rajarshi Ghosh1, Aylia Mohammadi2, Leonid Kruglyak13 and William S Ryu24*

Author Affiliations

1 Lewis-Sigler Institute for Integrative Genomics, Department of Ecology and Evolutionary Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA

2 Department of Physics, University of Toronto, St George Street, Toronto, Canada

3 Howard Hughes Medical Institute, Princeton University, Washington Road, Princeton, NJ 08544, USA

4 Donnelly Centre, University of Toronto, College Street, Toronto, Canada

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BMC Biology 2012, 10:85  doi:10.1186/1741-7007-10-85

Published: 31 October 2012

Additional files

Additional file 1:

Movie S1. Escape behavior of a N2 animal to ΔT = 0.4°C.

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Additional file 2:

Movie S2. Escape behavior of a N2 animal to ΔT = 9.1°C.

Format: MOV Size: 568KB Download file

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Additional file 3:

Table S1. Proportion of the variance explained by the first six principal components. At each ΔT this amounts to ≥ 0.95.

Format: DOCX Size: 37KB Download file

Open Data

Additional file 4:

Movie S3. Escape behavior of an akIs11 animal to ΔT = 9.1°C.

Format: MOV Size: 429KB Download file

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Open Data

Additional file 5:

Table S2. List of strains for thermal stimulus assay and the number of animals used to extract the behavioral parameters.

Format: DOCX Size: 77KB Download file

Open Data