Table 2 |
|||||
|
GO enrichment for the different groups of genes identified in the transcriptome and translatome comparison |
|||||
|
GO term |
Genes in GO term |
Group |
Genes in group |
P-value |
In group and term |
|
|
|||||
|
Response to oxidative stress |
83 |
++ |
142 |
6.1·10-9 |
14 |
|
|
|||||
|
Response to stress |
813 |
++ |
142 |
7.9·10-18 |
60 |
|
|
|||||
|
Protein unfolding |
3 |
++ |
142 |
0.002 |
2 |
|
|
|||||
|
Protein refolding |
17 |
++ |
142 |
0.0006 |
4 |
|
|
|||||
|
Protein folding |
113 |
++ |
142 |
0.0003 |
10 |
|
|
|||||
|
Ribosome biogenesis |
355 |
-- |
138 |
2.5·10-67 |
83 |
|
|
|||||
|
Ribosomal large subunit biogenesis |
73 |
-- |
138 |
5.3·10-26 |
27 |
|
|
|||||
|
Ribosomal small subunit biogenesis |
52 |
-- |
138 |
1.4·10-15 |
17 |
|
|
|||||
|
Ribosome assembly |
69 |
-- |
138 |
7.7·10-24 |
25 |
|
|
|||||
|
Ribosomal large subunit assembly |
39 |
-- |
138 |
2.8·10-12 |
13 |
|
|
|||||
|
Ribosomal small subunit assembly |
16 |
-- |
138 |
1.2·20-6 |
6 |
|
|
|||||
|
Ribosome localization |
43 |
-- |
138 |
3.5·10-9 |
11 |
|
|
|||||
|
Translation |
721 |
-- |
138 |
4.0·10-11 |
47 |
|
|
|||||
|
Regulation of translation |
190 |
-- |
138 |
3.8·10-9 |
21 |
|
|
|||||
|
Regulation of translational fidelity |
15 |
-- |
138 |
5.0·10-2 |
2 |
|
|
|||||
|
Response to drug |
120 |
+- |
88 |
0.09 |
3 |
|
|
|||||
|
Drug transport |
20 |
+- |
88 |
0.0007 |
3 |
|
|
|||||
|
Multidrug transport |
11 |
+- |
88 |
0.0001 |
3 |
|
|
|||||
|
Response to toxin |
31 |
+- |
88 |
0.002 |
3 |
|
|
|||||
|
Response to chemical stimulus |
457 |
+- |
88 |
0.02 |
9 |
|
|
|||||
|
Transposition, RNA mediated |
71 |
+- |
88 |
9.0·10-9 |
9 |
|
|
|||||
|
Transposition |
74 |
+- |
88 |
1.3·10-8 |
9 |
|
|
|||||
|
Direct positive ++, direct negative -- and inverse +-; GO enrichment for each group was done using the R package GOstats; the P-values for the processes described in the text are indicated. |
|||||
|
Paredes et al. BMC Biology 2012 10:55 doi:10.1186/1741-7007-10-55 |
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