Table 2

GO enrichment for the different groups of genes identified in the transcriptome and translatome comparison

GO term

Genes in GO term

Group

Genes in group

P-value

In group and term


Response to oxidative stress

83

++

142

6.1·10-9

14


Response to stress

813

++

142

7.9·10-18

60


Protein unfolding

3

++

142

0.002

2


Protein refolding

17

++

142

0.0006

4


Protein folding

113

++

142

0.0003

10


Ribosome biogenesis

355

--

138

2.5·10-67

83


Ribosomal large subunit biogenesis

73

--

138

5.3·10-26

27


Ribosomal small subunit biogenesis

52

--

138

1.4·10-15

17


Ribosome assembly

69

--

138

7.7·10-24

25


Ribosomal large subunit assembly

39

--

138

2.8·10-12

13


Ribosomal small subunit assembly

16

--

138

1.2·20-6

6


Ribosome localization

43

--

138

3.5·10-9

11


Translation

721

--

138

4.0·10-11

47


Regulation of translation

190

--

138

3.8·10-9

21


Regulation of translational fidelity

15

--

138

5.0·10-2

2


Response to drug

120

+-

88

0.09

3


Drug transport

20

+-

88

0.0007

3


Multidrug transport

11

+-

88

0.0001

3


Response to toxin

31

+-

88

0.002

3


Response to chemical stimulus

457

+-

88

0.02

9


Transposition, RNA mediated

71

+-

88

9.0·10-9

9


Transposition

74

+-

88

1.3·10-8

9


Direct positive ++, direct negative -- and inverse +-; GO enrichment for each group was done using the R package GOstats; the P-values for the processes described in the text are indicated.

Paredes et al. BMC Biology 2012 10:55   doi:10.1186/1741-7007-10-55

Open Data