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Open Access Correspondence

Re-analysis of the larval testis data on meiotic sex chromosome inactivation revealed evidence for tissue-specific gene expression related to the drosophila X chromosome

Maria D Vibranovski1*, Yong E Zhang12, Claus Kemkemer1, Hedibert F Lopes3, Timothy L Karr4 and Manyuan Long1*

Author Affiliations

1 Department of Ecology and Evolution, The University of Chicago, 1101 East 57th Street, Chicago, IL 60637, USA

2 Key Laboratory of the Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beichen West Road, Chaoyang District, Beijing 100101, PR China

3 The University of Chicago Booth School of Business, 5807 South Woodlawn Ave., Chicago, IL 60637, USA

4 Center for Evolutionary Medicine and Informatics and Center for Infectious Diseases and Vaccinology, The Biodesign Institute, Arizona State University, 1001 South McAllister Ave., Tempe, AZ 85287, USA

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BMC Biology 2012, 10:49  doi:10.1186/1741-7007-10-49

Published: 12 June 2012

Additional files

Additional file 1:

Figures S1-S3.

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Additional file 2:

Normalized testis developmental expression. Normalized expression (log2 based) from each testis developmental stage [32] for each Drosophila transcript with corresponding chromosomal location in xls format ('CG identification: transcript number').

Format: XLS Size: 10.6MB Download file

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Additional file 3:

Input for re-plot of Figure 4 in[32]. Re-plots are shown in Figure 3A and 3B.

Format: XLSX Size: 18KB Download file

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Additional file 4:

Tissue specific gene dataset. List of tissue-specific genes obtained through Flyatlas [33] expression (Methods and [32]). Each excel sheet corresponds to one analyzed adult tissue: midgut, malpigian tubules, accessory glands, salivary gland, head, ovary, and testis. Minimal fold between one tissue against all other tissues analyzed is shown for < 2, < 5, and < 10. Sex-bias is shown for all genes as: M, male-biased; F, female-biased; and U, unbiased.

Format: XLS Size: 1MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data