Additional file 4.

Alignment of EF-hand domains I, III, and IV of select photoprotein and photoprotein-like sequences. Important calcium ligand residues in the 12-residue calcium binding loops within each EF-hand domain are indicated with black triangles. Columns of residues are shaded as in Figure 2. Species are abbreviated as follows: Ac = Aequorea coerulescens; Aque = Amphimedon queenslandica; Cg = Clytia gregarium; Mc = Mitrocoma cellularia; Mlei = Mnemiopsis leidyi; Nvec = Nematostella vectensis; Og = Obelia geniculata.

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Schnitzler et al. BMC Biology 2012 10:107   doi:10.1186/1741-7007-10-107