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Model parameter descriptions and values |
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| Parameter |
Description |
Source |
Distributions |
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| Beta Distribution |
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| Mean |
Alpha (Beta) |
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| pSTEMI |
Probability of chest pain patients with ST-elevation myocardial infarction |
Trial data: audited patients with ST-elevation myocardial infarction/all patients with chest pain |
0.036 |
4800 (130000) |
| pACSdisc |
Probability of being discharged with ACS at a hospital with no CPU |
External data [8] |
0.012 |
7.55 (621.82) |
| Incmort |
Probability of inadvertent discharge upon ACS mortality, compared to admission |
External data [9] |
0.03 |
10.92 (353.1) |
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| Normal Distribution |
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| Mean |
Standard Error |
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| mortSTEMI |
Mortality of ST-elevation myocardial infarction at hospitals with no CPU |
Modelled from trial onset to needle time data using Boersma equation [7] |
0.1003 |
0.0004 |
| CPUdisc |
Effect of CPU availability upon probability of being discharged with ACS |
Trial data: effect of CPU upon (re)admission of initially discharged chest pain patients |
1.256 |
0.1962 |
| cpu_STEMI |
CPU availability impact upon mortality from ST-elevation myocardial infarction |
Modelled from trial onset to needle time data using Boersma equation |
0.0007 |
0.0013 |
| routQALY |
QALYs accrued up to six months after initial attendance at a hospital with no CPU |
Trial data: Area under the curve for health utility for all patients attending a hospital with no active CPU |
0.318 |
0.0038 |
| cpuQALY |
Effect of CPU availability upon QALYs accrued up to six months after initial attendance |
Trial data: Effect of CPU availability upon area under the curve for health utility |
0.0084 |
0.0129 |
| ltQALY |
Lifetime QALYs accrued by a typical patient with coronary heart disease |
External data: Vergel et al [6] |
6.829 |
0.3401 |
| routCOST |
Costs up to six months after initial attendance at a hospital with no CPU |
Trial data: Mean cost per patient for all attending a hospital with no CPU |
2405 |
63.5216 |
| cpuCOST |
Effect of CPU availability upon costs up to six months after initial attendance |
Trial data: Effect of CPU availability upon mean cost per patient |
-31 |
219.647 |
| ltCOST |
Lifetime costs of care for a typical patient with coronary heart disease |
External data: Vergel et al [6] |
10,079 |
2200 |
Oluboyede et al. BMC Health Services Research 2008 8:174 doi:10.1186/1472-6963-8-174 |
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