Table 2

Treatment Intensification Rates, Baseline Risk Factor Levels, Declines and Adjusted Differences During Follow-up - Study vs. Control Centers, Eligible Patients, by Priority Level
Study (n = 4 sites) Control (n = 4 sites)
Priority Number Eligible Patients Intensified within 3 months Baseline Mean Risk Factor Level

Unadjusted

Risk Factor

Decline

Number Eligible Patients Intensified within 3 months Baseline Mean Risk Factor Level

Unadjusted

Risk Factor

Decline

Adjusted

Study-Control Risk Factor Differences

(95% CI)

1: SBP ≥ 140 3,080 34.1 153.2 13.6 2,905 30.6 153.0 13.4 0.73
(-1.40, 2.83)
2: LDL-c ≥ 130 2,431 28.0 153.1 24.9 1,789 22.7 153.9 23.8 -2.63
(-6.73, 1.48)
3: A1c ≥ 9% 1,318 29.5 10.2 1.0 1,059 28.8 10.2 1.2 -0.02
(-0.36, 0.32)
4:SBP 130-139£ 3,878 22.9 138.5 6.0 3,583 22.0 138.5 5.0 -0.00
(-1.25, 1.26)
5: LDL-c 100-129 4,876 20.5 111.4 10.1 3,526 19.1 111.3 8.9 -0.83
(-4.10, 2.44)
6. A1c 7-8.9% 3,750 26.3 7.5 0 3,007 26.9 7.5 0 0.03
(-0.10, 0.16)

Based on the last value recorded before follow-up begins; i.e., the value that qualified patient for treatment intensification.

Based on the first value recorded after 3 months follow-up; if no values recorded between 3 and 12 months follow-up, the latest value recorded during first 3 months follow-up was used. No values were available during follow-up for 3%, 10%, and 14% of blood pressure, A1c, and LDL-c tests, respectively.

From repeated measures models using all available values during follow-up,with adjustment for age, gender, race-ethnicity, baseline risk factor value, number of medications for the risk factor at baseline, and days of follow-up at time of each measurement. Negative value indicates that the adjusted difference favored the study group group during follow-up.

p < 0.001 for study vs. control comparison.

£ Only patients with diabetes mellitus and/or chronic kidney disease were eligible for the target of SBP <130 mmHg.

Selby et al.

Selby et al. BMC Health Services Research 2012 12:183   doi:10.1186/1472-6963-12-183

Open Data