Table 2

The input values for clinical options for lung cancer detection derived from a literature and internet search

CLINICAL OPTIONS

SN

SP

Cost($)

Reference

PMID


TSGF

0.869

0.911

100.00

Newland Biotech [21]

N/A

NSE

0.4617

0.9323

100.00

Newland Biotech [21]

N/A

CA-125

0.5643

0.8472

100.00

Newland Biotech [21]

N/A

SELDI (serum)

0.869

0.8

100.00

Yang et al., 2005 [22]

16029516

TLP

0.667

0.8

100.00

Tarro et al., 2005 [23]

15389637

CA-19-9

0.333

1

100.00

Tarro et al., 2005 [23]

15389637

CYFRA 21-1

0.111

1

100.00

Tarro et al., 2005 [23]

15389637

CEA

0

1

100.00

Tarro et al., 2005 [23]

15389637

anti-Rc

0.2

0.98

100.00

Bazhin et al., 2004 [24]

15084384

LIFE bronchoscopy

0.68

0.696

100.00

Hirsch et al., 2001 [25]

11562389

WLB bronchoscopy

0.219

0.783

100.00

Hirsch et al., 2001 [25]

11562389

methylation in at least 1 of 5 tumor suppressor genes

0.495

0.85

100.00

Fujiwara et al., 2005 [26]

15709192

CT-guided fine-needle aspirate biopsy

0.82

1

100.00

Wallace et al., 2002 [27]

12461267

x-ray determinate only

0.54

0.99

100.00

Gavelli & Giampalma, 2000 [28]

11147625

x-ray indeterminate

0.84

0.9

100.00

Gavelli & Giampalma, 2000 [28]

11147625


Shi and Lyons-Weiler BMC Medical Informatics and Decision Making 2007 7:23   doi:10.1186/1472-6947-7-23

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