Table 2 |
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|
The input values for clinical options for lung cancer detection derived from a literature and internet search |
|||||
|
CLINICAL OPTIONS |
SN |
SP |
Cost($) |
Reference |
PMID |
|
|
|||||
|
TSGF |
0.869 |
0.911 |
100.00 |
Newland Biotech [21] |
N/A |
|
NSE |
0.4617 |
0.9323 |
100.00 |
Newland Biotech [21] |
N/A |
|
CA-125 |
0.5643 |
0.8472 |
100.00 |
Newland Biotech [21] |
N/A |
|
SELDI (serum) |
0.869 |
0.8 |
100.00 |
Yang et al., 2005 [22] |
16029516 |
|
TLP |
0.667 |
0.8 |
100.00 |
Tarro et al., 2005 [23] |
15389637 |
|
CA-19-9 |
0.333 |
1 |
100.00 |
Tarro et al., 2005 [23] |
15389637 |
|
CYFRA 21-1 |
0.111 |
1 |
100.00 |
Tarro et al., 2005 [23] |
15389637 |
|
CEA |
0 |
1 |
100.00 |
Tarro et al., 2005 [23] |
15389637 |
|
anti-Rc |
0.2 |
0.98 |
100.00 |
Bazhin et al., 2004 [24] |
15084384 |
|
LIFE bronchoscopy |
0.68 |
0.696 |
100.00 |
Hirsch et al., 2001 [25] |
11562389 |
|
WLB bronchoscopy |
0.219 |
0.783 |
100.00 |
Hirsch et al., 2001 [25] |
11562389 |
|
methylation in at least 1 of 5 tumor suppressor genes |
0.495 |
0.85 |
100.00 |
Fujiwara et al., 2005 [26] |
15709192 |
|
CT-guided fine-needle aspirate biopsy |
0.82 |
1 |
100.00 |
Wallace et al., 2002 [27] |
12461267 |
|
x-ray determinate only |
0.54 |
0.99 |
100.00 |
Gavelli & Giampalma, 2000 [28] |
11147625 |
|
x-ray indeterminate |
0.84 |
0.9 |
100.00 |
Gavelli & Giampalma, 2000 [28] |
11147625 |
|
|
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|
Shi and Lyons-Weiler BMC Medical Informatics and Decision Making 2007 7:23 doi:10.1186/1472-6947-7-23 |
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