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Open Access Research article

Automatic identification and normalization of dosage forms in drug monographs

Jiao Li and Zhiyong Lu*

Author Affiliations

National Library of Medicine, Bethesda, MD 20894, USA

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BMC Medical Informatics and Decision Making 2012, 12:9  doi:10.1186/1472-6947-12-9

Published: 15 February 2012

Abstract

Background

Each day, millions of health consumers seek drug-related information on the Web. Despite some efforts in linking related resources, drug information is largely scattered in a wide variety of websites of different quality and credibility.

Methods

As a step toward providing users with integrated access to multiple trustworthy drug resources, we aim to develop a method capable of identifying drug's dosage form information in addition to drug name recognition. We developed rules and patterns for identifying dosage forms from different sections of full-text drug monographs, and subsequently normalized them to standardized RxNorm dosage forms.

Results

Our method represents a significant improvement compared with a baseline lookup approach, achieving overall macro-averaged Precision of 80%, Recall of 98%, and F-Measure of 85%.

Conclusions

We successfully developed an automatic approach for drug dosage form identification, which is critical for building links between different drug-related resources.