## Figure 4.
Variation of total phenytoin, adjusted phenytoin, and free phenytoin with respect
to patient age. (A) Variation of the difference between PHT_{total/10 }and PHT_{free }with respect to patient age. All data from chronologically first phenytoin measurements
in 756 patients. The dashed line is from linear regression: [PHT_{total/10 }- PHT_{free}] = -0.394 + 0.0038*(patient age) (R^{2 }= 0.01). The 95% confidence intervals of the intercept is (-0.464, -0.372) and for
the slope is (-0.056, 0.064). (B) Variation of the difference between PHT_{free }and PHT_{adj_free }with respect to patient age is shown using same source of data as in (A). The dashed line is from linear regression: [PHT_{free }- PHT_{adj_free}] = 0.0838 + 0.0021 * age (R^{2 }= 0.004). The 95% confidence intervals of the intercept is (-0.0072, 0.174) and for
the slope is (-0.053, 0.057)
Krasowski and Penrod |